A new method for assessing powder flowability based on physical properties and cohesiveness of particles using a small quantity of samples

Characterising powder flowability can be a challenge if only small quantity of samples is available, e.g. pharmaceutical formulations. The paper focuses on new method for assessing based physical properties and cohesiveness particles using few grams powders. technique applies Bond number to represent cohesiveness, which detects particle adhesion at median size mechanical surface energy tester developed the Wolfson Centre. To establish method, correlations between numbers flow functions several powders measured shear cell have been explored empirically. With correlations, prediction model has not but also other such as compressibility, internal friction angles true angles. This investigation undertaken wide range materials from free-flowing very cohesive establishment group different types blind validation method. methodology shows promising results compressibility show good agreement against tester.